Dr Vikas Sud is a specialist registrar in general surgery within the Oxford Deanery and a member of Reuben College, University of Oxford. He completed his medical degree in India before gaining clinical experience across several centres in the United States. He then spent two years at the University of Pittsburgh, working in a hepatopancreatobiliary (HPB) research laboratory investigating the role of neutrophil extracellular traps (NETs) in liver disease. This work, primarily using experimental models, provided him with extensive laboratory expertise and a strong foundation in translational research.
At the University of Oxford, Dr Sud is now exploring how to reawaken the immune system to fight colorectal cancer that spreads to the liver. His research focuses on understanding why immune cells, particularly T cells, lose their ability to target these tumours and how this process can be reversed. Using advanced human liver models, he studies how removing harmful immune cell “nets” may restore immune activity and make resistant cancers responsive to immunotherapy. By bridging surgery and science, his goal is to develop new treatments that improve survival and inspire new approaches to combining surgery and immunotherapy for patients with limited options.